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ARN21929 - CAS 2230854-98-3

ARN21929 - CAS 2230854-98-3

MF-0063194-01

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Product Details

  • Bioactivity

    ARN21929 is a topoisomerase II (TopoisomeraseII) inhibitor with an IC50 of 4.5 μM. It exhibits favorable kinetic and thermodynamic solubility and metabolic stability. However, ARN21929 shows poor antiproliferative activity against A549, DU145, MCF7, HeLa, and A375 cells. It is useful for tumor research.

  • Target

    Topoisomerase

  • Related Pathways

    DNA Damage/DNA Repair

  • CAS Number

    2230753

  • Molecular Formula

    C18H16FN5

  • Molecular Weight

    321.35

  • SMILES

    FC=1C=CC=CC1NC2=NC(=NC3=C2CNCC3)C=4C=CN=CC4

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound