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ARN25062 - CAS 3036492-85-7

ARN25062 - CAS 3036492-85-7

SKU:MF-0063198-01

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  • Bioactivity

    ARN25062 is an inhibitor of the protein-protein interaction between Cdc42 and p21-activated kinase (PAK) . It inhibits the proliferation of SKM28, SK-MEL-3, WM3248, and A375 melanoma cells (IC50s = 6.1, 4.6, 9.3, and 5.1 μM, respectively) and SW480 colon cancer cells (IC50 = 5.9 μM) .

  • Target

    Ras

  • Related Pathways

    MAPK

  • CAS Number

    3036492-85-7

  • Molecular Formula

    C22H21F3N4

  • Molecular Weight

    398.4

  • SMILES

    FC(F)(F)C=1C=CC=C(C1)NC=2N=C(N=C(C2)C=3C=CC=CC3)C4CCNCC4

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound