Aromatase-IN-4 - CAS 3060588-16-8

Aromatase-IN-4 (Compound 6a) is an inhibitor of the enzyme aromatase. It displays anticancer properties, with GI50 values for different cell lines as follows: 2.95 μM for MDAMB-231, 3.35 μM for MCF-7, 2.27 μM for A-549, 8.46 nM for NCI-H23, and 1.56 μM for A-498. Aromatase-IN-4 effectively blocks the estrogen production that depends on aromatase.

Cytochromes P450

Metabolism

3060564

C23H18N6

378.429

N=1C=CC=C(C1)NC2=NC=C(C=C2)NC=3C=CC(=CC3)C4=NC=5C=CC=CC5N4

-20°C

Ice Packs

Small Compound