ARP-100 - CAS 704888-90-4

ARP-100 (MMP-2 Inhibitor III) is a potent and selective matrix metalloproteinase MMP-2 inhibitor (IC50=12 nM) . ARP-100 interacts with the S1' pocket of MMP-2 and exhibits anti-invasive properties in an in vitro invasion Matrigel model. ARP-100 has low inhibitory activity against MMP-1 (>50 μM), MMP-3 (4.5 μM), MMP-7 (>50 μM) and MMP-9 (0.2 μM) [1][2].

MMP

Proteases/Proteasome

704888-90-4

0.9834

C17H20N2O5S

364.42

CC(C)ON(CC(=O)NO)S(=O)(=O)c1ccc(cc1)-c1ccccc1

-20°C

Ice Packs

Small Compound