ART0380 - CAS 2267316-76-5

ART0380 is a potent, selective, orally available, ATP-competitive ATR kinase inhibitor (IC50=51.7 nM) with antitumor activity for the study of ataxia telangiectasia mutated (ATM) cancer.

ATM/ATR

PI3K/Akt/mTOR signaling, DNA Damage/DNA Repair

2267316-76-5

>99.99%

C18H24N6O2S

388.49

C[C@H]1N(CCOC1)C2=NC(C3=CC=NC(N)=C3)=NC(N=S(C4CC4)(C)=O)=C2

-20°C

Ice Packs

Small Compound