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Molfinity

ART812 - CAS 2607138-82-7

ART812 - CAS 2607138-82-7

MF-0015608-01

$120.88 USD
$120.88 USD
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Product Details

  • Bioactivity

    ART812 is an orally active inhibitor of DNA polymerase Polθ, possessing an IC50 value of 7.6 nM. Additionally, ART812 exhibits a cell-based microhomology-mediated end joining (MMEJ) IC50 value of 240 nM.

  • Target

    DNA/RNA Synthesis

  • Related Pathways

    Cell Cycle/Checkpoint, DNA Damage/DNA Repair

  • CAS Number

    2607049

  • Purity

    0.9932

  • Molecular Formula

    C19H16ClF4N3O4

  • Molecular Weight

    461.79

  • SMILES

    CN(C(=O)[C@@H]1[C@H](O)[C@H](O)C(=O)N1c1cc(cc(C)n1)C(F)(F)F)c1ccc(F)c(Cl)c1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound