Articaine - CAS 23964-58-1

Articaine (Hoe-045 free base), an amide anesthetic featuring an ester group, effectively relieves pain by reversibly binding to the α-subunit of the voltage-gated sodium channels located in the nerve's inner cavity. Furthermore, Articaine mitigates LPS-induced acute kidney injury through the suppression of NF-κB activation and inhibition of the NLRP3 inflammasome pathway.

Sodium Channel, Others, NOD-like Receptor (NLR), NF-κB

Immunology/Inflammation, Others, NF-κB, Membrane transporter/Ion channel

23905

C13H20N2O3S

284.37

CCCNC(C)C(=O)NC1=C(SC=C1C)C(=O)OC

-20°C

Ice Packs

Small Compound