AS-35 - CAS 108427-72-1

AS-35 is an orally effective, potent, and selective antagonist of leukotrienes, antagonizing LTC4-, LTD4-, and LTE4-induced ileum contractions with IC50 values of 8 nM, 4 nM, and 3 nM, respectively. It exhibits antiallergic activities.

Leukotriene Receptor

GPCR/G Protein

108354

0.9868

C21H20N6O4

420.42

O=C1C(=CN=C2C(=CC=CN12)COC3=CC=C(C(=O)C)C(O)=C3CCC)C4=NN=NN4

-20°C

Ice Packs

Small Compound