1 1

Molfinity

AS2863619 - CAS 2241300-51-4

AS2863619 - CAS 2241300-51-4

MF-0017498-01

$133.06 USD
$133.06 USD
Sale Sold out
Taxes included.
Size
View full details

Product Details

  • Bioactivity

    AS2863619 is an oral inhibitor of cyclin-dependent kinase 8 (CDK8) and CDK19. Inhibition of CDK8/19 can enhance the activation of STAT5, thereby activating the Foxp3 gene. It can convert antigen-specific effector/memory T cells into Foxp3+ regulatory T cells to study various immune diseases.

  • Target

    STAT, CDK

  • Related Pathways

    JAK/STAT signaling, Stem Cells, Cell Cycle/Checkpoint

  • CAS Number

    2241245

  • Purity

    >99.99%

  • Molecular Formula

    C16H14Cl2N8O

  • Molecular Weight

    405.24

  • SMILES

    Cl.Cl.Cc1nc2ccc(cc2[nH]1)-n1c(nc2cnccc12)-c1nonc1N

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound