ASCT2-IN-1 - CAS 3032651-18-3

ASCT2-IN-1 (compound 20k) is an inhibitor of ASCT2, demonstrating IC50 values of 5.6 μM in A549 cells and 3.5 μM in HEK293 cells. It induces apoptosis and inhibits tumor growth.

Apoptosis, Autophagy, ASCT, mTOR

Membrane transporter/Ion channel, Autophagy, PI3K/Akt/mTOR signaling, Apoptosis

3032630

C36H32Cl2N2O4

627.56

C(N(CC1=C(OCC#CC2=CC=C(Cl)C=C2)C=CC=C1)CC[C@@H](C(O)=O)N)C3=C(OCC#CC4=CC=C(Cl)C=C4)C=CC=C3

-20°C

Ice Packs

Small Compound