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ASK1-IN-3 - CAS 2426705-19-1
ASK1-IN-3 - CAS 2426705-19-1
SKU:MF-0063326-01
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$1,927.85 USD
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$1,927.85 USD
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Product Details
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Bioactivity
ASK1-IN-3 is a highly potent and selective inhibitor of ASK1 kinase, demonstrating an IC 50 of 33.8 nM. This compound also exhibits inhibitory effects on various cell cycle regulating kinases. ASK1-IN-3 showcases remarkable induction of apoptosis in HepG2 cancer cells and displays potent activity in arresting the cell cycle [1].
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Target
Others, MAPK, Apoptosis
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Related Pathways
Apoptosis, Others, MAPK
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CAS Number
2426685
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Molecular Formula
C18H18N8O2
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Molecular Weight
378.39
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SMILES
[C@H](CO)(C)N1C(=NN=C1)C=2N=C(NC(NC=3C=C4N(N3)C=CC=C4)=O)C=CC2
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound