ASK1-IN-8 - CAS 2570985-89-4

ASK1-IN-8 (Compound 35) is an orally active inhibitor of apoptosis signal-regulating kinase 1 (ASK1) with an IC50 value of 1.8 nM. In a mouse liver injury model induced by Acetaminophen, ASK1-IN-8 significantly reduces plasma alanine aminotransferase (ALT) levels, offering liver protection. This compound is useful for research in liver disease-related fields.

ASK

Apoptosis

2570892

C26H32N8O2

488.585

O=C1N(C2=NC(=CC=C2)C3=NN=CN3C(C)C)CCN1C4=CC=C(C=C4)N5CCC(C(=O)NC)CC5

-20°C

Ice Packs

Small Compound