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Molfinity

ASM-IN-3 - CAS 2342576-75-2

ASM-IN-3 - CAS 2342576-75-2

MF-0063334-01

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Product Details

  • Bioactivity

    ASM-IN-3 (Compound 21b) is a selective acid sphingomyelinase (ASM) inhibitor that can penetrate the blood-brain barrier, with an IC50 of 3.37 μM against purified human ASM. By inhibiting ASM activity in the hippocampus and promoting neurogenesis, ASM-IN-3 alleviates depressive-like behavior in reserpine-induced depressive rats.

  • Target

    Phospholipase

  • Related Pathways

    Metabolism

  • CAS Number

    2342499

  • Molecular Formula

    C17H13ClN2O4

  • Molecular Weight

    344.75

  • SMILES

    O=C(NO)C=1ON=C(OCC2=CC=C(C=C2)C=3C=CC(Cl)=CC3)C1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound