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Molfinity

ASP2453 - CAS 2241719-73-1

ASP2453 - CAS 2241719-73-1

SKU:MF-0015246-01

Regular price $120.88 USD
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  • Bioactivity

    ASP2453 is a potent, selective, and covalent inhibitor of KRAS G12C that inhibits the Son of Sevenless (SOS) -mediated interaction between KRAS G12C and Raf with an IC50 value of 40 nM.

  • Target

    Ras, ERK, Kras

  • Related Pathways

    MAPK, GPCR/G Protein

  • CAS Number

    2241645

  • Purity

    0.9971

  • Molecular Formula

    C40H48F3N7O4

  • Molecular Weight

    747.85

  • SMILES

    COCCCN1CCC(CC1)Oc1nc(N2CCC3(CN(C3)C(=O)C=C)CC2)c2cc(C3CC3)c(c(OCC(F)(F)F)c2n1)-c1c(C)ccc2[nH]ncc12

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound