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ASP2453 - CAS 2241719-73-1
ASP2453 - CAS 2241719-73-1
SKU:MF-0015246-01
Regular price
$120.88 USD
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$120.88 USD
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Product Details
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Bioactivity
ASP2453 is a potent, selective, and covalent inhibitor of KRAS G12C that inhibits the Son of Sevenless (SOS) -mediated interaction between KRAS G12C and Raf with an IC50 value of 40 nM.
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Target
Ras, ERK, Kras
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Related Pathways
MAPK, GPCR/G Protein
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CAS Number
2241645
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Purity
0.9971
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Molecular Formula
C40H48F3N7O4
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Molecular Weight
747.85
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SMILES
COCCCN1CCC(CC1)Oc1nc(N2CCC3(CN(C3)C(=O)C=C)CC2)c2cc(C3CC3)c(c(OCC(F)(F)F)c2n1)-c1c(C)ccc2[nH]ncc12
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound