Aspirin - CAS 50-78-2

Aspirin is an orally active, selective, and irreversible inhibitor of COX-1 and COX-2 with IC50 values of 5 and 210 μg/mL, respectively. It induces apoptosis, inhibits NF-κB activation and platelet prostaglandin synthesis, thereby preventing thrombosis. Additionally, it acts as a histone deacetylase inhibitor that upregulates p21, exhibiting anti-inflammatory, antipyretic, analgesic, and anti-platelet aggregation activities. Aspirin is commonly used to induce gastric ulcer models.

COX, Autophagy, Mitophagy, Virus Protease

Autophagy, Microbiology/Virology, Neuroscience, Immunology/Inflammation

-30

>99.99%

C9H8O4

180.16

CC(=O)OC1=CC=CC=C1C(O)=O

-20°C

Ice Packs

Small Compound