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Molfinity

AST 487 - CAS 630124-46-8

AST 487 - CAS 630124-46-8

MF-0019795-01

$33.17 USD
$33.17 USD
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Product Details

  • Bioactivity

    AST 487 (NVP-AST 487) is a RET kinase inhibitor, inhibiting RET autophosphorylation and activation of downstream effectors. It also can inhibit Flt-3.

  • Target

    FLT, VEGFR, c-RET, c-Kit, Bcr-Abl

  • Related Pathways

    Tyrosine Kinase/Adaptors, Cytoskeletal Signaling, Apoptosis, Angiogenesis

  • CAS Number

    630070

  • Purity

    0.9956

  • Molecular Formula

    C26H30F3N7O2

  • Molecular Weight

    529.56

  • SMILES

    C(C1=C(C(F)(F)F)C=C(NC(NC2=CC=C(OC=3C=C(NC)N=CN3)C=C2)=O)C=C1)N4CCN(CC)CC4

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound