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Aszonapyrone A - CAS 83103-08-6

Aszonapyrone A - CAS 83103-08-6

SKU:MF-0048152

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  • Bioactivity

    Aszonapyrone A is a meroditerpene fungal metabolite that has been found in Neosartorya and has diverse biological activities.1,2,3 It inhibits the growth of MCF-7, NCI H460, and A375-C5 cancer cells (GI50s = 13.6, 11.6, and 10.2 μM, respectively) .1 Aszonapyrone A is active against multidrug-resistant isolates of S. aureus, E. faecalis, and E. faecium (MICs = 8, 16, and 16 μg/ml, respectively) and inhibits S. aureus biofilm formation.2 It is also active against P. falciparum in vitro (IC50 = 1.34 μg/ml) .3

  • Target

    Others, Antifungal, Antibacterial

  • Related Pathways

    Microbiology/Virology, Others

  • CAS Number

    83103-08-6

  • Molecular Formula

    C28H40O5

  • Molecular Weight

    456.623

  • SMILES

    [H][C@@]12CC[C@@]3(C)[C@H](Cc4c(O)cc(C)oc4=O)C(=C)CC[C@]3([H])[C@@]1(C)CC[C@H](OC(C)=O)C2(C)C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Natural Product