AT7867 dihydrochloride - CAS 1431697-86-7

AT7867 dihydrochloride is a potent ATP-competitive inhibitor of Akt1/Akt2/Akt3 and p70S6K/PKA kinase, with IC50 values of 32 nM/17 nM/47 nM and 85 nM/20 nM, respectively. It induces pharmacodynamic changes and inhibits human tumor xenograft growth.

Akt, Others, PKA, S6 Kinase

PI3K/Akt/mTOR signaling, Tyrosine Kinase/Adaptors, MAPK, Others, Cytoskeletal Signaling

1431604

C20H22Cl3N3

410.77

Cl.Cl.Clc1ccc(cc1)C1(CCNCC1)c1ccc(cc1)-c1cn[nH]c1

-20°C

Ice Packs

Small Compound