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Atabecestat - CAS 1200493-78-2

Atabecestat - CAS 1200493-78-2

MF-0032092-01

$132.25 USD
$132.25 USD
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Product Details

  • Bioactivity

    Atabecestat (JNJ-54861911) is a potent, brain-penetrant, and orally active β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor that achieves robust and high CSF Aβ reduction, is well-tolerated, and displays sustained pharmacokinetic (PK) and pharmacodynamic (PD) characteristics. Atabecestat (JNJ-54861911) has the potential for Alzheimer's Disease treatment[1].

  • Target

    BACE, Beta-Secretase

  • Related Pathways

    Neuroscience

  • CAS Number

    1200413

  • Purity

    0.9977

  • Molecular Formula

    C18H14FN5OS

  • Molecular Weight

    367.4

  • SMILES

    C[C@]1(C=CSC(N)=N1)c1cc(NC(=O)c2ccc(cn2)C#N)ccc1F

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound