ATC 0175 hydrochloride - CAS 510733-97-8

ATC 0175 hydrochloride is an orally active melanocyte concentrating hormone 1 receptor antagonist that is potent and selective. ATC 0175 hydrochloride has affinity for MCH1R, MCH2R, MCH1, 5-HT2B receptors and 5-HT1A receptors with IC50s of 13.5 nM, >10,000 nM, 13 nM, 9.66 nM and 16.9 nM, respectively. ATC 0175 hydrochloride exhibits antidepressant and anxiolytic effects in animal models. aTC 0175 can be used to study depression and/or anxiety disorders.

5-HT Receptor, GPCR, Melanin-concentrating Hormone Receptor (MCHR)

GPCR/G Protein, Endocrinology/Hormones, Neuroscience

510628

0.9998

C23H26ClF2N5O

461.93

N(C)(C)C=1C2=C(N=C(N[C@H]3CC[C@@H](NC(=O)C4=CC(F)=C(F)C=C4)CC3)N1)C=CC=C2.Cl

-20°C

Ice Packs

Small Compound