Atecegatran metoxil - CAS 433937-93-0

Atecegatran Metoxil (Atecegatran Fexenetil , AZD0837) is an oral direct thrombin inhibitor, which currently in clinical development for the prevention of stroke and systemic embolic events in patients with atrial fibrillation. AZD0837 is a selective and reversible direct thrombin inhibitor and is a bioconverted to AR-H067637.AZD0837 is well tolerated in healthy male subjects at a single oral dose (15-750 mg) and demonstrated favorable PK properties and reproducible effects on in vitro coagulation time variables, supporting further clinical development.

Others, Thrombin

Proteases/Proteasome, Others

433844

C22H23ClF2N4O5

496.89

C([C@H](O)C1=CC(OC(F)F)=CC(Cl)=C1)(=O)N2[C@H](C(NCC3=CC=C(C(NOC)=N)C=C3)=O)CC2

-20°C

Ice Packs

Small Compound