ATIC-IN-1 - CAS 1402453-15-9

ATIC-IN-1 (compound 14) is an inhibitor targeting the dimerization of Aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC), with a K i of 685 nM. This dimerization is crucial for the enzyme's AICAR transformylase function. Additionally, ATIC-IN-1 exhibits anti-tumor properties by reducing cell proliferation and cell division rates [1].

Others

Others

1402453-15-9

C21H33N7O5

463.53

[C@@H](CC1=CC=C(N(=O)=O)C=C1)(NC([C@H](CCCNC(=N)N)NC(C)=O)=O)C(N(CC)CC)=O

-20°C

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Small Compound