Atigotatug (FUT8-KO) - CAS 2733581-82-1

Atigotatug (FUT8-KO) is a monoclonal antibody expressed in CHO cells, where the fucosyltransferase 8 gene (FUT8) has been knocked out. The absence of fucose enhances the antibody's ADCC effect. It targets the fucosylated ganglioside GM1 (fuc-GM1) and is an IgG1κ type humanized antibody. Atigotatug can induce immune-mediated tumor cell death, such as in small-cell lung cancer.

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2733581-82-1

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Inhibitory Antibodies