Atiprimod dihydrochloride - CAS 130065-61-1

JAK2 inhibitor (IC50 = 397 nM) . Also inhibits STAT3 and STAT5 phosphorylation. Inhibits cell growth and induces apoptosis in cells expressing the JAK2V617F mutation.

Apoptosis, Caspase, p62, Autophagy, STAT, ATG, JAK, Others, ROS

Others, Angiogenesis, Apoptosis, Immunology/Inflammation, Tyrosine Kinase/Adaptors, JAK/STAT signaling, Proteases/Proteasome, Autophagy, Chromatin/Epigenetic, Stem Cells

130003

C22H46Cl2N2

409.52

Cl.Cl.CCCC1(CCC)CCC2(CCN(CCCN(CC)CC)C2)CC1

-20°C

Ice Packs

Small Compound