ATR-258 - CAS 2301983-88-8

ATR-258 is a GRK2-biased partial agonist of β2AR. It acts as a competitive antagonist of β1AR and exhibits weak partial agonist activity on β3AR at a concentration of 10 μM. ATR-258 enhances glycemic control and reduces lipid accumulation in obese mice with minimal side effects. It is applicable in research on type 2 diabetes (T2DM) .

Adrenergic Receptor

GPCR/G Protein, Neuroscience

2301887

C11H17FN2O

212.26

[C@@H](CNC(C)(C)C)(O)C=1C=C(F)C=NC1

-20°C

Ice Packs

Small Compound