Atraric acid - CAS 4707-47-5

Atraric acid derivatives as a new chemical lead structure for novel therapeutic compounds as AR antagonists, that can be used for prophylaxis or treatment of prostatic diseases. It inhibits PTP1B activity in a dose-dependent manner with IC50 values of 51.5 uM, suggest that atraric acid has potential to treat diabetes.

Phosphatase, Androgen Receptor, p38 MAPK, NF-κB, NO Synthase

Endocrinology/Hormones, Metabolism, MAPK, NF-κB, Immunology/Inflammation

4655

0.9959

C10H12O4

196.2

COC(=O)C1=C(O)C(C)=C(O)C=C1C

-20°C

Ice Packs

Natural Product