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ATWLPPR Peptide - CAS 272121-15-0

ATWLPPR Peptide - CAS 272121-15-0

SKU:MF-0063705-01

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  • Bioactivity

    ATWLPPR Peptide is a biologically active peptide functioning as a specific antagonist to VEGFR2/KDR. It binds to VEGFR2 (KDR/flk), thereby completely inhibiting VEGF binding to KDR and blocking VEGF-induced angiogenesis in vivo. Moreover, it selectively inhibits human endothelial cell proliferation in vitro and effectively abolishes VEGF-induced angiogenesis in vivo.

  • Target

    VEGFR

  • Related Pathways

    Tyrosine Kinase/Adaptors, Angiogenesis

  • CAS Number

    272106

  • Molecular Formula

    C40H61N11O9

  • Molecular Weight

    839.98

  • SMILES

    C([C@@H](C(N[C@H](C(=O)N1[C@H](C(=O)N2[C@H](C(N[C@@H](CCCNC(=N)N)C(O)=O)=O)CCC2)CCC1)CC(C)C)=O)NC([C@@H](NC([C@H](C)N)=O)[C@@H](C)O)=O)C=3C=4C(NC3)=CC=CC4

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Peptide