ATX inhibitor 11 - CAS 2485779-27-7

ATX inhibitor 11 is a potent inhibitor of ATX (autotaxin) (IC50: 2.7 nM) . ATX inhibitor 11 alleviates the severity of fibrotic tissue and effectively reduces the deposition of α-SMA, a biomarker of fibrosis, in a mouse model of fibrosis. ATX inhibitor 11 can be used to study lung fibrosis.

Others, PDE

Others, Metabolism

2485745

C32H35N5O6

585.65

N(C(OCC=1C=C2C(=CC1)OCO2)=O)C=3N4C(=NC3CC)C(C)=CC(=C4)C5=CC=C(C(=O)N6CCN(CCO)CC6)C=C5

-20°C

Ice Packs

Small Compound