ATX inhibitor 27 - CAS 2023027-81-6

ATX inhibitor 27 (Compound 31) is an ATX inhibitor. It demonstrates IC50 values of 13 nM against human autotaxin (hATX) and 23 nM against lysophosphatidylcholine (LPC) . By inhibiting the ATX enzyme, ATX inhibitor 27 reduces LPA levels in the body. This compound is applicable in research related to ATX-LPA-associated conditions such as inflammation, neurodegenerative disorders, and cancer.

PDE, LPL Receptor

Metabolism, GPCR/G Protein

2022940

C26H26ClN5O3

491.97

N#CC1=CC=C(C=C1Cl)CN(C(=O)CN2C=NC=3C=CC(=CC3C2=O)C4CCN(C(=O)C)CC4)C

-20°C

Ice Packs

Small Compound