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Aumitin - CAS 946293-78-3
Aumitin - CAS 946293-78-3
SKU:MF-0014995-01
Regular price
$54.10 USD
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$54.10 USD
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Product Details
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Bioactivity
Aumitin, a diaminopyrimidine-based autophagy inhibitor, dose-dependently inhibits starvation- and rapamycin-induced autophagy with IC50s of 0.12 μM and 0.24 μM, respectively [1], and also inhibits mitochondrial respiration by targeting complex I.
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Target
Autophagy
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Related Pathways
Autophagy
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CAS Number
946212
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Purity
0.9913
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Molecular Formula
C24H20ClN5O
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Molecular Weight
429.9
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SMILES
Cc1cc(Nc2ccccc2)nc(Nc2ccc(NC(=O)c3ccccc3Cl)cc2)n1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound