Aurantio-obtusin - CAS 67979-25-3

1. Biotransformation of glucoAurantio-obtusin towards Aurantio-obtusin increased the toxicity of irinotecan through increased inhibition of SN-38 glucuronidation. 2. Aurantio-obtusin, stimulated chemotactic migration of MC3T3-E1 osteoblast cells in a concentration-dependent manner. Besides migration, the compound stimulated osteoblast differentiation and mineralization. 3. Aurantio-obtusin is a promising osteoanabolic compound of natural origin with potential therapeutic applications in the prevention of osteoporosis and other metabolic bone diseases.

COX, Others, TNF

Apoptosis, Immunology/Inflammation, Others, Neuroscience

67979-25-3

0.9945

C17H14O7

330.29

COc1c(O)cc2C(=O)c3cc(C)c(O)c(OC)c3C(=O)c2c1O

-20°C

Ice Packs

Natural Product