Aurora A/PKC-IN-1 - CAS 2143100-98-3

Aurora A/PKC-IN-1 (Compound 2e) is a potent dual inhibitor of Aurora A (AurA) and PKC (α, β1, β2, θ), exhibiting inhibitory activity on AurA (IC50: 6.9 nM) and PKCα (IC50: 16.9 nM), and demonstrating anti-proliferative and anti-metastatic effects on breast cancer cells.

Others, PKC, Aurora Kinase

Others, Cytoskeletal Signaling, Chromatin/Epigenetic, Cell Cycle/Checkpoint

2142999

C16H14N6OSe2

464.24

O=C1N([Se]C=2C1=CC=CC2)C3=NC(NC4CC[Se]C4)=C5C(=N3)N=CN5

-20°C

Ice Packs

Small Compound