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Aurora kinase ligand-1 - CAS 1907679-70-2
Aurora kinase ligand-1 - CAS 1907679-70-2
SKU:MF-0119198-01
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Product Details
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Bioactivity
Aurora kinaseligand-1 (Compound I-4) is an AURKB PROTAC ligand designed to target aurora kinase B. It can conjugate with an E3 ligase ligand and a linker to form the AURKB PROTAC degrader MS44, which is applicable in cancer research.
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Target
Ligands for Target Protein for PROTAC, Aurora Kinase
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Related Pathways
PROTAC, Chromatin/Epigenetic, Cell Cycle/Checkpoint
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CAS Number
1907607
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Molecular Formula
C24H26FN7O3
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Molecular Weight
479.51
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SMILES
O=C(NC=1C=CC=C(F)C1)CC2=NNC(=C2)NC=3N=CN=C4C=C(OCCCNCCO)C=CC43
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
PROTAC