AUTAC2 - CAS 2241669-08-7

AUTAC2, an autophagy-mediated degrader (AUTAC) targeting FKBP12, comprises an FBnG (p-Fluorobenzyl Guanine) and an SLF (c ligand of FKBP) moiety. The SLF component binds non-covalently to FKBP12 [1].

Others, AUTACs, Autophagy

Autophagy, Others, PROTAC

2241669-08-7

C61H81FN10O14S

1229.42

C(N1C2=C(N=C1SC[C@@H](C(NCCCOCCOCCOCCCNC(CCC(NC3=CC([C@H](OC(=O)C4N(C(C(C(CC)(C)C)=O)=O)CCCC4)CCC5=CC(OC)=C(OC)C=C5)=CC=C3)=O)=O)=O)NC(C)=O)C(=O)N=C(N)N2)C6=CC=C(F)C=C6

-20°C

Ice Packs

PROTAC