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Molfinity

AV-412 - CAS 451493-31-5

AV-412 - CAS 451493-31-5

MF-0004519-01

$37.66 USD
$37.66 USD
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Product Details

  • Bioactivity

    AV-412 (MP412) is an EGFR inhibitor for EGFR, EGFR T790M, EGFR L858R, EGFR L858R/T790M, and ErbB2, with IC50 values of 0.75, 0.79, 0.5, 2.3, and 19 nM, respectively.

  • Target

    EGFR

  • Related Pathways

    Angiogenesis, Tyrosine Kinase/Adaptors, JAK/STAT signaling

  • CAS Number

    451457

  • Purity

    0.9992

  • Molecular Formula

    C41H44ClFN6O7S2

  • Molecular Weight

    851.41

  • SMILES

    Cc1ccc(cc1)S(O)(=O)=O.Cc1ccc(cc1)S(O)(=O)=O.CN1CCN(CC1)C(C)(C)C#Cc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)C=C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound