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Molfinity

AV-412 free base - CAS 451492-95-8

AV-412 free base - CAS 451492-95-8

MF-0041474

$59.34 USD
$59.34 USD
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Product Details

  • Bioactivity

    AV-412 free base is an EGFR inhibitor (IC50s: 0.75, 0.79, 0.5, 2.3, 19 nM for EGFR, EGFR (T790M), EGFR (L858R), EGFR (L858R/T790M) and ErbB2) .

  • Target

    EGFR

  • Related Pathways

    Angiogenesis, Tyrosine Kinase/Adaptors, JAK/STAT signaling

  • CAS Number

    451389

  • Molecular Formula

    C27H28ClFN6O

  • Molecular Weight

    507

  • SMILES

    CN1CCN(CC1)C(C)(C)C#Cc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)C=C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound