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Molfinity

Avacopan - CAS 1346623-17-3

Avacopan - CAS 1346623-17-3

MF-0011794-01

$36.16 USD
$22.75 USD $36.16 USD
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Product Details

  • Bioactivity

    Avacopan (CCX168) is a C5aR antagonist (IC50=0.1 nM) with selective and oral activity. Avacopan blocks the action of C5a and prevents the development of GN induced by anti-myeloperoxidase antibodies in a mouse model of AAV. Avacopan can be used to treat anti-neutrophil cytoplasmic antibody (ANCA) -related vasculitis.

  • Target

    Complement System

  • Related Pathways

    Immunology/Inflammation

  • CAS Number

    1346623-17-3

  • Purity

    0.999

  • Molecular Formula

    C33H35F4N3O2

  • Molecular Weight

    581.64

  • SMILES

    C(=O)(N1[C@H]([C@@H](C(NC2=CC(C(F)(F)F)=C(C)C=C2)=O)CCC1)C3=CC=C(NC4CCCC4)C=C3)C5=C(C)C=CC=C5F

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound