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Molfinity

Avasimibe - CAS 166518-60-1

Avasimibe - CAS 166518-60-1

SKU:MF-0012556-01

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  • Bioactivity

    Avasimibe (PD-148515) is an orally bioavailable inhibitor of acyl-Coenzyme A: cholesterol acyltransferase (ACAT, IC50: 3.3 μM) that prevents cholesterol deposition in the arterial wall. It also inhibits human P450 isoenzymes CYP2C9/1A2/2C19 (IC50: 2.9/13.9/26.5 μM) .

  • Target

    Cytochromes P450, Acyltransferase

  • Related Pathways

    Metabolism

  • CAS Number

    166457

  • Purity

    0.9991

  • Molecular Formula

    C29H43NO4S

  • Molecular Weight

    501.72

  • SMILES

    CC(C)c1cc(C(C)C)c(CC(=O)NS(=O)(=O)Oc2c(cccc2C(C)C)C(C)C)c(c1)C(C)C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound