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Molfinity

AWD12-281 sodium - CAS 247584-21-0

AWD12-281 sodium - CAS 247584-21-0

SKU:MF-0063773-01

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  • Bioactivity

    AWD 12-281 is a selective phosphodiesterase 4 (PDE4) inhibitor for the treatment of lung inflammation using inhalative administration. AWD 12-281 Is Active in a New Guinea-Pig Model of Allergic Skin Inflammation Predictive of Human Skin Penetration and Suppresses Both Th1 and Th2 Cytokines in Mice. AWD 12-281 is a very promising drug candidate not only for the treatment of lung inflammation using inhalative administration but also for the treatment of atopic dermatitis.

  • Target

    Others

  • Related Pathways

    Others

  • CAS Number

    247563

  • Molecular Formula

    C22H13Cl2FN3NaO3

  • Molecular Weight

    480.25

  • SMILES

    ClC1=CN=CC(Cl)=C1NC(C(C(C2=C3)=CN(CC4=CC=C(C=C4)F)C2=CC=C3[O-])=O)=O.[Na+]

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound