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Molfinity

AX-53802 - CAS 1008482-71-0

AX-53802 - CAS 1008482-71-0

MF-0063776-01

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Product Details

  • Bioactivity

    AX-53802 is a ferroptosis (ferroptosis) inducer targeting GPX4, with an IC50 of 0.34 μM. It forms a covalent bond with GPX4, initiating membrane translocation upon binding. In combination with FAK/Src inhibitors, AX-53802 enhances cell death. This compound is applicable in cancer research.

  • Target

    Ferroptosis, Glutathione Peroxidase

  • Related Pathways

    Apoptosis, Metabolism

  • CAS Number

    1008411

  • Molecular Formula

    C23H21FN2O4

  • Molecular Weight

    408.422

  • SMILES

    O=C(C#C)N(C1=CC=C2OCOC2=C1)C(C(=O)NC3CCCC3)C=4C=CC=CC4F

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound