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Axitinib - CAS 319460-85-0

Axitinib - CAS 319460-85-0

MF-0005174-01

$34.67 USD
$34.67 USD
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Product Details

  • Bioactivity

    Axitinib (AG-013736) is a multi-targeted tyrosine kinase inhibitor that inhibits VEGFR1, VEGFR2, VEGFR3, and PDGFRβ (IC50=4/20/0.4/2 nM) . Axitinib has antitumor activity and is used in the treatment of renal cell carcinoma.

  • Target

    PDGFR, VEGFR, c-Kit

  • Related Pathways

    Angiogenesis, Tyrosine Kinase/Adaptors

  • CAS Number

    319375

  • Purity

    0.9981

  • Molecular Formula

    C22H18N4OS

  • Molecular Weight

    386.47

  • SMILES

    C(=C/C1=CC=CC=N1)\C=2C=3C(=CC(SC4=C(C(NC)=O)C=CC=C4)=CC3)NN2

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound