AXL-IN-14 - CAS 2947506-65-0

AXL-IN-14 is a potent, orally active inhibitor of AXL with an IC50 of 0.8 nM that effectively suppresses Gas6/AXL-mediated cell migration and invasion, reduces the expression of p-AXL and p-AKT proteins, and demonstrates anti-tumor activity [1].

TAM Receptor

Tyrosine Kinase/Adaptors

2947441

C32H24F2N4O4

566.55

CC(C)N1C=C(C(=O)C(=C1)C(=O)NC2=CC(=C(C=C2)OC3=C4C(=NC=C3)NC5=CC=CC=C5O4)F)C6=CC=C(C=C6)F

-20°C

Ice Packs

Small Compound