Axl-IN-19 - CAS 2870696-46-9

Axl-IN-19 (Compound 68) is a selective inhibitor of AXL, a membrane-bound receptor tyrosine kinase, with an IC50 of 5.3 nM and a cellular KD of 6.8 nM. In rats, Axl-IN-19 demonstrates favorable pharmacokinetic properties, featuring low clearance and moderate bioavailability, and is applicable for cancer research.

TAM Receptor

Tyrosine Kinase/Adaptors

2870641

C31H33N5O2

507.63

C(N(C)C)(=O)C1=CC=C(C=2C3=CC(C=4C=C5CC[C@@H](N6C7CC6COC7)CCC5=CC4)=CN=C3NN2)C=C1

-20°C

Ice Packs

Small Compound