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Molfinity

AY 9944 - CAS 366-93-8

AY 9944 - CAS 366-93-8

MF-0032107-01

$36.16 USD
$22.75 USD $36.16 USD
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Product Details

  • Bioactivity

    AY 9944 is a specific cholesterol biosynthesis inhibitor that targets the 7-dehydrocholesterol Δ7-reductase (DHCR7) enzyme (IC50=13 nM) . At high doses, AY 9944 also inhibits sterol Δ7-Δ8 isomerase in cultured embryos, leading to the accumulation of cholest-8-en-3β-ol[1][2][3]. Additionally, AY 9944 causes hypocholesterolemia and accumulation of 7DHC.

  • Target

    Others

  • Related Pathways

    Others

  • CAS Number

    366-93-8

  • Purity

    0.9965

  • Molecular Formula

    C22H30Cl4N2

  • Molecular Weight

    464.3

  • SMILES

    Cl.Cl.Clc1ccccc1CNC[C@H]1CC[C@H](CNCc2ccccc2Cl)CC1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound