AZ-GHS-22 - CAS 1143020-91-0

AZ-GHS-22 is an inverse agonist of the growth hormone secretagogue receptor 1a (GHS-R1a), which is also known as the ghrelin receptor.1It binds to GHS-R1a with an IC50value of 0.77 nM. AZ-GHS-22 decreases food intake in mice by 54% in the first two hours after administration of a 100 mg/kg dose.

Others, GHSR

GPCR/G Protein, Others

1142929

C27H33ClN6O5S2

621.17

N(C(NC(=O)C1=CC(=CC=C1Cl)N2CCOCC2)=O)C=3SC=4C(N3)=CC=C(S(CCCN5CCN(C)CC5)(=O)=O)C4

-20°C

Ice Packs

Small Compound