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AZ-PFKFB3-67 - CAS 1704741-11-6

AZ-PFKFB3-67 - CAS 1704741-11-6

MF-0063831-01

$41.39 USD
$41.39 USD
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Product Details

  • Bioactivity

    AZ-PFKFB3-67 is a potent and selective PFKFB3 kinase inhibitor with an IC50=11nM for PFKFB3, reduces MCL-1, and inhibits angiogenesis by decreasing lactic acid production and ATP levels in endothelial cells (ECs) in tube-forming assays, and has neuroprotective effects.

  • Target

    Others, Bcl-2 Family, Phosphatase, Glucokinase

  • Related Pathways

    Metabolism, Apoptosis, Others

  • CAS Number

    1704724

  • Purity

    0.9979

  • Molecular Formula

    C26H25N5O3

  • Molecular Weight

    455.51

  • SMILES

    C(#N)C=1C=2C(N(CC=3C(C)=NOC3C)C1)=CC=C(OC4=CC=C(NC(=O)[C@@H]5CCCN5)C=C4)C2

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound