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AZ12601011 - CAS 2748337-86-0

AZ12601011 - CAS 2748337-86-0

MF-0004527-01

$106.25 USD
$106.25 USD
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Product Details

  • Bioactivity

    AZ12601011 is an orally active, selective and potent TGFBR1 kinase inhibitor.AZ12601011 inhibits the release of inflammatory factors, interleukin (IL) -1β, IL-6 and tumor necrosis factor-α, and inhibits the growth of breast tumors.AZ12601011 directly binds to TGF-βR1 and blocks downstream Smad3 activation, which can be used to prevent renal fibrosis.

  • Target

    ALK, TGF-beta/Smad

  • Related Pathways

    Tyrosine Kinase/Adaptors, Angiogenesis, Stem Cells

  • CAS Number

    2748251

  • Purity

    0.9881

  • Molecular Formula

    C19H15N5

  • Molecular Weight

    313.36

  • SMILES

    N=1C=CC2=C(C1)C=CN2C3=NC(=NC4=C3CCC4)C5=NC=CC=C5

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound