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AZ1495 - CAS 2196204-23-4
AZ1495 - CAS 2196204-23-4
SKU:MF-0016105-01
Regular price
$97.31 USD
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$97.31 USD
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Product Details
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Bioactivity
AZ1495 is an oral active inhibitor of Interleukin-1 receptor associated kinase 4 (IRAK4), with IC50 values of 5 nM and 23 nM for IRAK4 and IRAK1, respectively. Which Shows activity in treatment of mutant MYD88L265P diffuse large B-cell lymphoma (DLBCL) .
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Target
IRAK, CDK, Haspin Kinase
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Related Pathways
Cell Cycle/Checkpoint, NF-κB, Immunology/Inflammation
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CAS Number
2196177
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Purity
0.9881
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Molecular Formula
C21H31N5O2
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Molecular Weight
385.5
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SMILES
C1CC(CCO1)c1c[nH]c2ncnc(N[C@H]3CC[C@@H](CC3)N3CCOCC3)c12
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound