Molfinity

AZ32 - CAS 2288709-96-4

SKU:MF-0019087-01

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Size 1 mg 5 mg 1 mL - 10 mM (in DMSO) 10 mg 25 mg 50 mg 100 mg

Product Details

Bioactivity
AZ32 is an orally bioavailable, blood-brain barrier-penetrating ATM inhibitor with an IC50 of <6.2 nM for the ATM enzyme and an IC50 of 0.31 μM for ATM in cells.
Target
ATM/ATR
Related Pathways
DNA Damage/DNA Repair, PI3K/Akt/mTOR signaling
CAS Number
2288609
Purity
0.9994
Molecular Formula
C20H16N4O
Molecular Weight
328.37
SMILES
CNC(=O)c1ccc(cc1)-c1cnc2cnc(cn12)-c1ccccc1
Storage Temperature
-20°C
Shipping Conditions
Ice Packs
Category
Small Compound