AZ3246 - CAS 2893978-54-4

AZ3246 is an orally active, selective inhibitor of HPK1 with an IC50 of less than 3 nM. It induces IL-2 secretion in T cells with an EC50 of 90 nM. AZ3246 also functions as a low-volume, low-clearance antitumor compound.

MAPK, Interleukin

MAPK, Immunology/Inflammation

2893920

C21H20F3N9O

471.438

O=C(N)C1=NC(=C(N=C1NC2=CN(N=C2C)CC(F)(F)F)C3CC3)C4=CN=CC5=C4N=CN5C

-20°C

Ice Packs

Small Compound